Make America Slim Again Ingredients — 11 Natural Compounds for Metabolic Support
What is Make America Slim Again? It is a liquid dietary supplement containing 11 carefully selected ingredients in a proprietary 550 mg blend, combining powerful botanical extracts with nutrient-dense bee-derived compounds. Each ingredient was chosen based on published clinical research and its potential to support healthy weight management, metabolic efficiency, and overall wellness.
The formula is anchored by Raw Wildflower Honey — a rare honey variety containing natural enzymes from raw honey that research suggests may help break down dietary fats. This unique foundation is enhanced by Berberine for AMPK activation, adaptogenic Holy Basil, and a comprehensive array of antioxidant-rich botanicals.
Other Ingredients: Water, Natural Flavors, Natural Colors, Glycerin, Stevia Extract, Potassium Sorbate
1. Berberine HCl Extract (8%) — Phellodendron amurense Bark
Berberine is a bioactive compound extracted from the bark of Phellodendron amurense, a tree native to Asia. It's been extensively studied for its ability to activate AMPK (AMP-activated protein kinase), often referred to as the "metabolic master switch."
Research published in Frontiers in Pharmacology (2025) suggests that Berberine activates AMPK, enhancing glucose uptake and promoting lipid metabolism. A separate study in the European Journal of Medical Research (June 2025) describes Berberine's multimodal anti-obesity mechanisms via AMPK activation, including effects on glucose regulation and fat metabolism.
Function: Activates AMPK, supports glucose uptake, promotes lipid metabolism, enhances insulin sensitivity
2. Kudzu Root Extract — Pueraria lobata (std. to 40% Isoflavones)
Kudzu Root (Pueraria lobata) has been used in traditional Chinese medicine for centuries. It's rich in isoflavones, particularly puerarin, which has been the subject of modern research for its potential effects on metabolism and body composition.
Research published in Bioscience, Biotechnology, and Biochemistry found that Pueraria flower extract reduced BMI and visceral fat area in obese adults over a 12-week period. The standardized 40% isoflavone content ensures a consistent, potent dose of these bioactive compounds.
Function: Contains puerarin; may support visceral fat reduction and healthy body composition
3. Holy Basil Extract (2.5% Ursolic Acid) — Ocimum sanctum Leaves
Holy Basil (Ocimum sanctum), also known as Tulsi, is a revered adaptogenic herb in Ayurvedic medicine. It contains ursolic acid, a pentacyclic triterpenoid that has attracted significant scientific interest for its potential effects on muscle and fat metabolism.
A study published in PLoS ONE (2012) found that ursolic acid increased skeletal muscle and brown fat while decreasing diet-induced obesity in mice. Additional research in Frontiers in Microbiology (2023) suggests ursolic acid may ameliorate obesity via gut microbiota alteration. As an adaptogen, Holy Basil also helps the body manage stress — a known factor in weight gain.
Function: Adaptogenic support; ursolic acid may influence muscle and fat metabolism
4. Royal Jelly
Royal Jelly is a nutrient-dense secretion produced by worker honeybees to feed queen bees. It's rich in proteins, fatty acids, vitamins (particularly B-complex), minerals, and unique compounds like 10-HDA (10-hydroxy-2-decenoic acid) that aren't found in other foods.
Research published in Nutrition Journal (2012) suggests that royal jelly ingestion over 6 months may improve lipoprotein metabolism. Its comprehensive nutritional profile supports cellular health, energy production, and overall metabolic function.
Function: Nutrient-dense bee secretion; may support lipid metabolism and cellular health
5. Bee Pollen
Bee Pollen is collected by honeybees from flower stamens and represents one of nature's most complete nutritional sources. It contains approximately 250 biologically active substances including proteins, amino acids, vitamins, minerals, enzymes, and antioxidants.
The nutritional density of bee pollen supports overall vitality and metabolic function. Its protein content helps maintain lean muscle mass during weight management efforts, while its antioxidant compounds help protect cells from oxidative stress.
Function: Nutritional density; proteins, vitamins, minerals, and antioxidants support overall wellness
6. Bee Propolis Extract (std. to 65% Propolis and 8% Flavones)
Propolis is a resinous substance bees collect from tree buds and sap flows. They use it to seal and protect the hive. For humans, propolis offers a rich source of flavonoids and phenolic compounds with potent antimicrobial, anti-inflammatory, and antioxidant properties.
The standardized extract contains 65% propolis and 8% flavones, ensuring a consistent level of these bioactive compounds. Research suggests propolis flavonoids may support metabolic health through their anti-inflammatory and antioxidant effects.
Function: Antimicrobial, anti-inflammatory, and antioxidant support via flavonoids
7. Raw Wildflower Honey — Base for Raw Wildflower Honey Blend
Raw Wildflower Honey serves as the natural base for this formula. Unlike processed honey, raw honey retains its natural enzymes, antioxidants, and bioactive compounds that support digestive comfort and overall wellness.
Research published in the International Journal of Obesity (2025) highlights that digestive enzymes play a crucial role in lipid metabolism. Raw honey contains various natural compounds that support digestive comfort and the body's natural digestive processes.
Function: Natural enzymes and antioxidants; base for this bee-derived blend; supports digestive comfort
8. Purple Carrot Powder
Purple Carrot Powder provides the distinctive color while delivering a concentrated dose of anthocyanins — potent antioxidant compounds responsible for the deep purple hue. These anthocyanins are among the most powerful antioxidants found in nature.
Anthocyanins have been studied for their potential to combat oxidative stress, support healthy inflammation responses, and protect cellular health. The vibrant color is a visual testament to the antioxidant power contained in every serving.
Function: Anthocyanins provide antioxidant protection and give the formula its distinctive purple color
9. Olive Leaf Extract (20% Oleuropein)
Olive Leaf Extract has been used medicinally for thousands of years, dating back to ancient Egypt. Modern research has identified oleuropein as its primary active compound, responsible for many of its health-supporting properties.
Research published in Nutrition, Metabolism and Cardiovascular Diseases (2025) found that olive leaf extract (250 mg/day for 8 weeks) improved body weight, BMI, and fat mass in obese women. The 20% oleuropein standardization ensures a potent, consistent dose of this researched compound.
Function: Antioxidant and anti-inflammatory; may support metabolic parameters and healthy body weight
10. Raspberry Seed
Raspberry seeds are an often-overlooked nutritional powerhouse. They're rich in dietary fiber, essential fatty acids (including omega-3 and omega-6), and bioactive compounds like ellagitannins and ellagic acid that support cellular health.
The fiber content of raspberry seeds supports digestive health and promotes feelings of fullness, while their antioxidant compounds help protect cells from oxidative damage. This makes raspberry seed a valuable addition to a comprehensive weight management formula.
Function: Fiber and bioactive compounds support digestive health and cellular protection
11. Sodium Alginate
Sodium Alginate is a natural polysaccharide extracted from brown seaweed. It's been widely studied for its unique ability to form a gel-like matrix when exposed to stomach acid, which may promote feelings of fullness and support portion control.
This gel-forming property makes sodium alginate a valuable tool for weight management support. By helping you feel satisfied with smaller portions, it complements the metabolic-supporting effects of the other ingredients.
Function: Derived from seaweed; may promote feelings of fullness and support satiety
Scientific References
- Frontiers in Pharmacology, 2025 — Berberine activates AMPK, enhancing glucose uptake and promoting lipid metabolism.
- European Journal of Medical Research, June 2025 — Berberine demonstrates multimodal anti-obesity mechanisms via AMPK activation.
- Bioscience, Biotechnology, and Biochemistry — Pueraria flower extract reduces BMI and visceral fat area in obese adults (12 weeks).
- Nutrition Journal, 2012 — Royal jelly ingestion for 6 months may improve lipoprotein metabolism.
- PLoS ONE, 2012 — Ursolic acid increases skeletal muscle and brown fat, decreases diet-induced obesity in mice.
- Frontiers in Microbiology, 2023 — Ursolic acid ameliorates obesity via gut microbiota alteration.
- Nutrition, Metabolism and Cardiovascular Diseases, 2025 — Olive leaf extract (250 mg/day, 8 weeks) improved body weight, BMI, and fat mass in obese women.
- International Journal of Obesity, 2025 — Pancreatic enzymes play a crucial role in lipid digestion and metabolism.
These references are provided for educational purposes. Individual results may vary. This product is not intended to diagnose, treat, cure, or prevent any disease.
Frequently Asked Questions About Make America Slim Again Ingredients
Are all ingredients in Make America Slim Again natural?
Yes. It's formulated with natural botanical extracts, bee-derived compounds, and natural flavors and colors. The formula contains no artificial stimulants, no synthetic fillers, and no harmful additives.
What is the proprietary blend amount?
It contains a proprietary blend of 550 mg per serving, combining all 11 active ingredients. The recommended dosage is 2 mL daily, preferably taken in the morning.
Is Make America Slim Again safe for people with bee allergies?
No. It contains multiple bee-derived ingredients including Royal Jelly, Bee Pollen, Bee Propolis, and Raw Wildflower Honey. Individuals with known allergies to bees or bee products should not use this supplement.
Can I take Make America Slim Again if I am on diabetes medication?
Because Berberine may affect blood sugar levels, individuals taking blood sugar medications should consult their healthcare provider before using this supplement. Don't discontinue or adjust any medication without professional guidance.
What makes Raw Wildflower Honey special?
Raw Wildflower Honey is a nutrient-rich ingredient that contains natural enzymes, antioxidants, and bioactive compounds. These natural compounds support digestive comfort and complement the body's nutrient absorption processes. Combined with the honey's natural antioxidant properties, this makes it a distinctive foundation for the weight management formula.